👉 The Nebraska Flu, also known as the H2N8 influenza pandemic of 1918, was a global outbreak of the influenza A subtype H2N8 that caused significant morbidity and mortality. What makes it unique is its unusual origin; unlike typical flu pandemics caused by avian influenza strains, the Nebraska Flu emerged from a human-to-human transmission in North America. The virus likely originated in pigs, where it underwent genetic reassortment, creating a novel strain that spread rapidly among humans. This pandemic was particularly devastating due to the lack of prior immunity in the population, resulting in high infection and death rates, especially among young adults. The Nebraska Flu serves as a stark reminder of the potential for influenza viruses to jump species and cause widespread public health crises.
